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Sandile Cele, a researcher at the Africa Health Research Institute in Durban, South Africa, works on the omicron variant of the COVID-19 virus Wednesday Dec. 15, 2021. An analysis of data from South Africa, where the new variant is driving a surge in infections, suggests the Pfizer vaccine offers less defense against infection from omicron and reduced, but still good, protection from hospitalization. (AP Photo/Jerome Delay)