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01 June 2010, Rome, Italy. Despite her husband's life-threatening disease, Mirella devoted her life to assisting Luigi, trying to be positive and reassuring, looking after him with intense love and respect. Everyday care, usually done in a few minutes, takes hours when it concerns someone with dementia. Mirella, 71, spent 43 years of her life with the only person she loved, with all of life's difficulties, laughter, and beautiful moments. But over the last six years things changed: Mirella lived with her husband Luigi¿s illness, Alzheimer¿s, and devoted her life to him as his caregiver. (Fausto Podavini) NO SALES, THIS MATERIAL IS FOR SINGLE USE PUBLICATIONS IN PRINT OR FOR A TEMPORARY ONLINE PUBLICATION, AND MAY BE USED EXCLUSIVELY TO PUBLICIZE THE 2013 WORLD PRESS CONTEST AND EXHIBITION. IT MAY NOT BE PUBLISHED AS PART OF AN ARTICLE OR ANY OTHER ITEM THAT CONTAINS NO DIRECT LINK TO WORLD PRESS PHOTO AND ITS ACTIVITIES. THE PICTURE MAY NOT BE CROPPED OR MANIPULATED IN ANY WAY. - KEYSTONE PROVIDES ACCESS TO THIS PUBLICLY DISTRIBUTED HANDOUT PHOTO. THE COPYRIGHT IS OWNED BY A THIRD PARTY ** This material is for single publications in print or for a temporary online publication, and may be used exclusively to publicize the 2013 World Press Photo contest and exhibition. It may not be published as part of an article or any other item that contains no direct link to World Press Photo and its activities without prior permission from the photographer or agency.