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AT THE MONASTIC CELL. PRAYER, 1915. ARTIST: DELLA-VOS-KARDOVSKAYA, OLGA LUDVIGOVNA (1875-1952)

At the Monastic Cell. Prayer, 1915. Found in the collection of the State Tretyakov Gallery, Moscow. At the Monastic Cell. Prayer, 1915. Artist: Della-Vos-Kardovskaya, Olga Ludvigovna (1875-1952) (KEYSTONE/HERITAGE IMAGES/FINE ART IMAGES)

MOSQUITO CELL INFECTED WITH A BACULOVIRUS, ELECTRON MICROGRAPH MICROGRAPH

Electron micrograph of the nucleus of a mosquito (Culex nigripalpus) cell infected with a baculovirus (family Baculoviridae). This family of viruses infects arthropods, and have been researched as a means of biological pest control. (KEYSTONE/SCIENCE PHOTO LIBRARY/Peggy Greb, US DEPARTMENT OF AGRICULTURE/SCIENCE PHOTO LIBRARY)

SCAR POST BASAL CELL CARCINOMA EXCISION

Editorial use only .Scar 2 months after a basal cell carcinoma (BCC) excision in a 68 year old female patient. BCC is one of the most common forms of skin cancer, and is most often caused by over-exposure to sunlight. The cancer usually starts as a small flat nodule and grows slowly, eventually breaking down at centre to form a shallow ulcer that persistently bleeds. Basal cell carcinomas rarely spread to other parts of the body. Treatment involves the surgical removal of the tumour and radiotherapy. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A WOMAN'S CHEEK

Not to be used for advertising or in a defamatory context .Nodular basal cell carcinoma (BCC) on the cheek of a 95 year old female patient. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. For a further image of this patient with this condition see SPL code C059/5433. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A MAN'S SCALP

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) on the scalp of a 81 year old male patient. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA OF PINNA IN A MALE PATIENT

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) of the pinna in a 81 year old male patient. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. BBC of the pinna typically presents as a painless, slow-growing, red bump on the skin of the ear. The lesion may bleed, or crust over, resembling an open sore. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. For another image of this patient with this condition see SPL code C059/5501. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA OF PINNA IN A MALE PATIENT

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) of the pinna in a 78 year old male patient. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. BBC of the pinna typically presents as a painless, slow-growing, red bump on the skin of the ear. The lesion may bleed, or crust over, resembling an open sore. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA OF PINNA IN A MALE PATIENT

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) of the pinna in a 81 year old male patient. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. BBC of the pinna typically presents as a painless, slow-growing, red bump on the skin of the ear. The lesion may bleed, or crust over, resembling an open sore. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. For another image of this patient with this condition see SPL code C059/5503. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A MAN'S CHEST

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) on the chest of a 78 year old male patient. This case is recurrent at the site of a previous excision. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. For an image of this patient with this condition 6 months previously see SPL code C059/5497. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A MAN'S HAND

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) on the hand of a 79 year old male patient. The growth is 18 millimetres in diameter. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. For a further image of this patient with this condition see SPL code C059/5433. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

SCAR AFTER BASAL CELL CARCINOMA EXCISION

Editorial use only .Scar following a basal cell carcinoma (BCC) excision in a 72 year old male patient. BCC is one of the most common forms of skin cancer, and is most often caused by over-exposure to sunlight. The cancer usually starts as a small flat nodule and grows slowly, eventually breaking down at centre to form a shallow ulcer that persistently bleeds. Basal cell carcinomas rarely spread to other parts of the body. Treatment involves the surgical removal of the tumour and radiotherapy. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A MAN'S CHEEK

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) on the cheek of a 86 year old female patient. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A MAN'S HAND

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) on the hand of a 79 year old male patient. The growth is 18 millimetres in diameter. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. For a further image of this patient with this condition see SPL code C059/5432. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A MAN'S CHEST

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) on the chest of a 78 year old male patient. This case is recurrent at the site of a previous excision. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. For an image of this patient with this condition 6 months later see SPL code C059/5499. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

BASAL CELL CARCINOMA ON A MAN'S BACK

Not to be used for advertising or in a defamatory context .Basal cell carcinoma (BCC) on the back of a 87 year old male patient. The growth is 18 millimetres in diameter. BCC is a form of skin cancer that starts in the basal cell, which is responsible for generating new skin cells as the old ones expire. The tumour may manifest as a small pink lump that appears shiny, translucent, or waxy. It could gradually increase in size and may also become crusty, bleed, or develop into an ulcer. BCC could also take the form of a scaly patch that appears red or brown. The leading cause of BCC is overexposure to ultraviolet (UV) light, particularly on sun-exposed areas of the body like the face, head, neck, and ears. It typically destroys surrounding tissue but seldom spreads to other areas of the body. BCC commonly afflicts fair-skinned adults, although in recent years the average age of onset has steadily decreased. Treatment options for BCC include radiotherapy, cryotherapy, cauterisation and surgical excision. (KEYSTONE/SCIENCE PHOTO LIBRARY/DR P. MARAZZI)

FOREIGN TERRORIST CELL MEMBERS DETAINED IN DAGESTAN, RUSSIA

RUSSIA, REPUBLIC OF DAGESTAN - APRIL 1, 2024: Officers of the Russian Federal Security Service (FSB) carry out an operation to detain foreign citizens, members of a terrorist cell. According to FSB reports, the citizens had been financing and providing weapons to the terrorists who attacked Crocus City Hall, and had also been plotting a terrorist attack in a crowded place in the city of Kaspiysk. Video grab. Best quality available. Russian Federal Security Service (KEYSTONE/TASS/Russian Federal Security Service)

FOREIGN TERRORIST CELL MEMBERS DETAINED IN DAGESTAN, RUSSIA

RUSSIA, REPUBLIC OF DAGESTAN - APRIL 1, 2024: Officers of the Russian Federal Security Service (FSB) carry out an operation to detain foreign citizens, members of a terrorist cell. According to FSB reports, the citizens had been financing and providing weapons to the terrorists who attacked Crocus City Hall, and had also been plotting a terrorist attack in a crowded place in the city of Kaspiysk. Video grab. Best quality available. Russian Federal Security Service (KEYSTONE/TASS/Russian Federal Security Service)

FOREIGN TERRORIST CELL MEMBERS DETAINED IN DAGESTAN, RUSSIA

RUSSIA, REPUBLIC OF DAGESTAN - APRIL 1, 2024: Officers of the Russian Federal Security Service (FSB) carry out an operation to detain foreign citizens, members of a terrorist cell. According to FSB reports, the citizens had been financing and providing weapons to the terrorists who attacked Crocus City Hall, and had also been plotting a terrorist attack in a crowded place in the city of Kaspiysk. Video grab. Best quality available. Russian Federal Security Service (KEYSTONE/TASS/Russian Federal Security Service)

MOBILITY CITY TECHNOLOGY MUSEUM IN ZARAGOZA

Filtration system for fuel cells. ....Mobility City Technology Museum in Zaha Hadid's Bridge (Bridge Pavilion), Zaragoza, Spain (KEYSTONE/VWPICS/Nano Calvo )

MOBILITY CITY TECHNOLOGY MUSEUM IN ZARAGOZA

Filtration system for fuel cells. ....Mobility City Technology Museum in Zaha Hadid's Bridge (Bridge Pavilion), Zaragoza, Spain (KEYSTONE/VWPICS/Nano Calvo )

JAIL-CELL

(Dreamstime/TNS) (KEYSTONE/NEWSCOM/Dreamstime)

AIRBUS ENGINEER WORKING ON HYDROGEN FUEL CELL

Editorial use only .Airbus engineer working on hydrogen fuel cell. To reduce the environmental impact of commercial aviation, Airbus launched the ZEROe project in 2020 to develop the world's first zero-emission commercial aircraft by 2035. Hydrogen fuel cells work by transforming the hydrogen into electricity through a chemical reaction. The by-product of the reaction is water vapour, resulting in almost zero emissions. (KEYSTONE/SCIENCE PHOTO LIBRARY/AIRBUS DEFENCE AND SPACE )

AIRBUS HYDROGEN FUEL CELL DEVELOPMENT

Editorial use only .Airbus hydrogen fuel cell development. Airbus have developed an experimental version of the powertrain called the 'iron pod'. This includes a electric motors and gearbox with an electromechanical load taking the place of a propeller. Under the ZEROe programme, Airbus intends to put a hydrogen-powered aircraft into service in the mid 2030s. At 1.2 MW output, the engine is sized for an aircraft capable of carrying 100 passengers on routes of 1,850 kilometres using a six-motor configuration. Hydrogen fuel cells work by transforming the hydrogen into electricity through a chemical reaction. The by-product of the reaction is water vapour, resulting in almost zero emissions. (KEYSTONE/SCIENCE PHOTO LIBRARY/AIRBUS DEFENCE AND SPACE )

MODEL OF HYDROGEN FUEL CELL ENGINE, ILLUSTRATION

Illustration of a model of a hydrogen fuel cell engine. To reduce the environmental impact of commercial aviation, Airbus launched the ZEROe project in 2020 to develop the world's first zero-emission commercial aircraft by 2035. Hydrogen fuel cells work by transforming the hydrogen into electricity through a chemical reaction. The by-product of the reaction is water vapour, resulting in almost zero emissions. (KEYSTONE/SCIENCE PHOTO LIBRARY/AIRBUS DEFENCE AND SPACE )

AIRBUS ENGINEERS WORKING ON HYDROGEN FUEL CELL

Editorial use only .Airbus engineers working on hydrogen fuel cell. To reduce the environmental impact of commercial aviation, Airbus launched the ZEROe project in 2020 to develop the world's first zero-emission commercial aircraft by 2035. Hydrogen fuel cells work by transforming the hydrogen into electricity through a chemical reaction. The by-product of the reaction is water vapour, resulting in almost zero emissions. (KEYSTONE/SCIENCE PHOTO LIBRARY/AIRBUS DEFENCE AND SPACE )

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x4000 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x2500 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x4000 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x2500 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x4000 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x2500 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

NERVE CELL IN ALZHEIMER'S DISEASE, TEM

Transmission electron micrograph (TEM) of a nerve cell (neuron) from a patient with Alzheimer's disease. This neurodegenerative disease is a common cause of dementia in the elderly. Its onset is marked by the formation of protein plaques in the brain. The symptoms include memory loss, personality changes and confusion. Magnification: x3,300 when printed at 10 centimetres wide. (KEYSTONE/SCIENCE PHOTO LIBRARY/THOMAS DEERINCK, NCMIR)

CELL INFECTED WITH HIV, SEM

Coloured scanning electron micrograph (SEM) of HIV particles (red) budding from the membrane of a HeLa host cell. HIV (human immunodeficiency virus) attacks CD4+ T-lymphocytes (specialised white blood cells), which are crucial in the body's immune system. It enters the cell and makes many copies of itself, which then destroy the cell as they emerge through its membrane. This severely weakens the immune system, causing AIDS (acquired immunodeficiency syndrome). Each virus is approximately 100 nanometres in diameter. (KEYSTONE/SCIENCE PHOTO LIBRARY/THOMAS DEERINCK, NCMIR)

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x2500 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

CHEMOTHERAPY INDUCED CELL DEATH, SEM

Chemotherapy induced cell death. Coloured scanning electron micrograph (SEM) of a cultured cancer cell (HeLa) treated with doxorubicin to cause necrosis. Doxorubicin is a type of chemotherapy drug called an anthracycline. Cell death can be programmed as in apoptosis or unregulated as in necrosis. Necrosis can be a dose or time related effect of this drug in cultured cancer cells. This method of death can trigger inflammation and harm healthy cells, which is why oncolgists strive to tip the balance towards apoptosis. Morphologically at SEM level, necrotic cells characteristically display ruptured plasma membrane, and cell lysis. The numerous visible holes are characteristic of early necrosis. Magnification: x4000 when printed at 10 centimetres wide. Specimen courtesy of Greg Towers, UCL. For a set of images showing the treated cells see C058/5931 to C058/5967. (KEYSTONE/SCIENCE PHOTO LIBRARY/STEVE GSCHMEISSNER)

HIV PARTICLES ON CELL SURFACE, TEM

Coloured transmission electron micrograph (TEM) of HIV particles (blue) budding from the membrane of a host cell. HIV (human immunodeficiency virus) attacks CD4+ T-lymphocytes (specialised white blood cells), which are crucial to the body's immune system. It enters the cell and makes many copies of itself, which then destroy the cell as they emerge through its membrane. This severely weakens the immune system, causing AIDS (acquired immunodeficiency syndrome). Magnification: x80,000 when printed at 10 centimetres wide. (KEYSTONE/SCIENCE PHOTO LIBRARY/THOMAS DEERINCK, NCMIR)

CELL PHONE BAN

A sign banning cell phones is stuck to a door in the German Bundestag in Berlin, March 11, 2024. (KEYSTONE/DPA/Florian Gaertner)

CELL PHONE BAN

A sign banning cell phones is stuck to a door in the German Bundestag in Berlin, March 11, 2024. (KEYSTONE/DPA/Florian Gaertner)

CELL PHONE BAN

A sign banning cell phones is stuck to a door in the German Bundestag in Berlin, March 11, 2024. (KEYSTONE/DPA/Florian Gaertner)

HUMAN SPERM CELL, ILLUSTRATION

Illustration of a human sperm cell. (KEYSTONE/SCIENCE PHOTO LIBRARY/THOMAS PARSONS)

HUMAN SPERM CELL, ILLUSTRATION

Illustration of a human sperm cell. (KEYSTONE/SCIENCE PHOTO LIBRARY/THOMAS PARSONS)

HUMAN SPERM CELL, ILLUSTRATION

Illustration of a human sperm cell. (KEYSTONE/SCIENCE PHOTO LIBRARY/THOMAS PARSONS)

HUMAN SPERM CELL, ILLUSTRATION

Illustration of a human sperm cell. (KEYSTONE/SCIENCE PHOTO LIBRARY/THOMAS PARSONS)

WHITE BLOOD CELL INTERACTING WITH KLEBSIELLA PNEUMONIAE BACTERIA, TEM

Coloured transmission electron micrograph (TEM) of a human neutrophil (red) containing ingested a Klebsiella pneumoniae bacterium (purple). Klebsiella is commonly found in human intestines and under normal conditions does not cause any harm. It can cause severe opportunistic infections however, especially in people receiving certain hospital treatments. These infections include pneumonia, meningitis, blood infections and infections of surgical wounds. It is resistant to multiple drugs, but infections can be treated with certain antibiotics. Neutrophils have several roles in the body's immune response, one being phagocytosis (ingestion) of foreign material such as this bacterium. (KEYSTONE/SCIENCE PHOTO LIBRARY/NATIONAL INSTITUTES OF HEALTH)

WHITE BLOOD CELL ATTACKING STREPTOCOCCUS PNEUMONIAE BACTERIA, SEM

Coloured scanning electron micrograph (SEM) of Streptococcus pneumoniae bacteria (green) being attacked by a white blood cell (orange). S. pneumoniae is a leading cause of pneumonia, which particularly affects the young and old, or otherwise immunocompromised people. It also causes middle ear infections (otitis media). Antibiotics are typically used to treat these infections. (KEYSTONE/SCIENCE PHOTO LIBRARY/CDC, NIAID)

WHITE BLOOD CELL INTERACTING WITH KLEBSIELLA PNEUMONIAE BACTERIA, SEM

Coloured scanning electron micrograph (SEM) of a neutrophil (white blood cell, blue) interacting with Klebsiella pneumoniae bacteria (orange). Klebsiella is commonly found in human intestines and under normal conditions does not cause any harm. It can cause severe opportunistic infections however, especially in people receiving certain hospital treatments. These infections include pneumonia, meningitis, blood infections and infections of surgical wounds. It is resistant to multiple drugs, but infections can be treated with certain antibiotics. (KEYSTONE/SCIENCE PHOTO LIBRARY/NIAID)

WHITE BLOOD CELL INTERACTING WITH KLEBSIELLA PNEUMONIAE BACTERIUM, SEM

Coloured scanning electron micrograph (SEM) of a neutrophil (white blood cell, blue) interacting with Klebsiella pneumoniae bacteria (red). Klebsiella is commonly found in human intestines and under normal conditions does not cause any harm. It can cause severe opportunistic infections however, especially in people receiving certain hospital treatments. These infections include pneumonia, meningitis, blood infections and infections of surgical wounds. It is resistant to multiple drugs, but infections can be treated with certain antibiotics. (KEYSTONE/SCIENCE PHOTO LIBRARY/NIAID)

WHITE BLOOD CELL INTERACTING WITH KLEBSIELLA PNEUMONIAE BACTERIUM, SEM

Coloured scanning electron micrograph (SEM) of a neutrophil (white blood cell, grey) interacting with Klebsiella pneumoniae bacteria (yellow). Klebsiella is commonly found in human intestines and under normal conditions does not cause any harm. It can cause severe opportunistic infections however, especially in people receiving certain hospital treatments. These infections include pneumonia, meningitis, blood infections and infections of surgical wounds. It is resistant to multiple drugs, but infections can be treated with certain antibiotics. (KEYSTONE/SCIENCE PHOTO LIBRARY/NIAID)

T-MOBILE STORE IN NEW YORK

A T-Mobile store in Midtown Manhattan in New York on Sunday, March 3, 2024. (Â Richard B. Levine) Photo via Newscom (KEYSTONE/NEWSCOM/Richard B. Levine)

PROTEIN-SECRETING CELL, TEM

Coloured transmission electron micrograph (TEM) of a protein-secreting cell (serous cell). The cytoplasm is full of enlarged rough endoplasmic reticulum (RER) cisterns (red) showing connections with the nuclear envelope. The nucleus (light green) shows heterochromatin (blue), euchromatin (green) and a nucleolus (magenta). (KEYSTONE/SCIENCE PHOTO LIBRARY/JOSE CALVO )

CERVICAL CANCER CELL, SEM

Cervical cancer cell, coloured scanning electron micrograph (SEM). The cervix is the lower part of the womb, also called the neck of the womb, and comprises part of the woman's reproductive system. Cervical cancer is more common in younger women and one of the main causes is a persistent infection of certain types of the human papilloma virus (HPV). Magnification: x2800 when printed at 10cm wide. (KEYSTONE/SCIENCE PHOTO LIBRARY/ANNE E. WESTON)

PROTEIN-SECRETING CELL, TEM

Coloured transmission electron micrograph (TEM) of a protein-secreting cell (serous cell). The cytoplasm is full of rough endoplasmic reticulum (RER) cisterns (blue). The nucleus (light brown) shows a nucleolus (dark blue) and a nuclear envelope (red). The cell rests on a basement membrane (pink) of an epithelial cell. (KEYSTONE/SCIENCE PHOTO LIBRARY/JOSE CALVO )

PROTEIN-SECRETING CELL, TEM

Coloured transmission electron micrograph (TEM) of a protein-secreting cell (serous cell). The cytoplasm (light blue) is full of rough endoplasmic reticulum (RER) cisterns (yellow). The nucleus (light green) shows the nuclear envelope (red), heterochromatin (blue), euchromatin (green), nucleolus (magenta) and a nuclear envelope (red). (KEYSTONE/SCIENCE PHOTO LIBRARY/JOSE CALVO )

CERVICAL CANCER CELL, SEM

Cervical cancer cell, coloured scanning electron micrograph (SEM). The cervix is the lower part of the womb, also called the neck of the womb, and comprises part of the woman's reproductive system. Cervical cancer is more common in younger women and one of the main causes is a persistent infection of certain types of the human papilloma virus (HPV). Magnification: x2800 when printed at 10cm wide. (KEYSTONE/SCIENCE PHOTO LIBRARY/ANNE E. WESTON)

CERVICAL CANCER CELL, SEM

Cervical cancer cell, coloured scanning electron micrograph (SEM). The cervix is the lower part of the womb, also called the neck of the womb, and comprises part of the woman's reproductive system. Cervical cancer is more common in younger women and one of the main causes is a persistent infection of certain types of the human papilloma virus (HPV). Magnification: x2800 when printed at 10cm wide. (KEYSTONE/SCIENCE PHOTO LIBRARY/ANNE E. WESTON)

CAR T CELL IMMUNOTHERAPY, ILLUSTRATION

Illustration of CAR (chimeric antigen receptor) T cell immunotherapy, a process that is being developed to treat cancer. T cells (shown in cross-section), part of the body's immune system, are taken from the patient and have their DNA (deoxyribonucleic acid) modified by viruses (round) so that they produce chimeric antigen receptor (CAR) proteins (green). These proteins will be specific to the patient's cancer. They have an extracellular receptor component and an internal signalling and co-stimulatory domain. The modified T cells are then multiplied in the laboratory before being reintroduced to the patient. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

CAR T CELL IMMUNOTHERAPY, ILLUSTRATION

Illustration of CAR (chimeric antigen receptor) T cell immunotherapy, a process that is being developed to treat cancer. T cells (shown in cross-section), part of the body's immune system, are taken from the patient and have their DNA (deoxyribonucleic acid) modified by viruses (round) so that they produce chimeric antigen receptor (CAR) proteins (red). These proteins will be specific to the patient's cancer. They have an extracellular receptor component and an internal signalling and co-stimulatory domain. The modified T cells are then multiplied in the laboratory before being reintroduced to the patient. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

CAR T CELL IMMUNOTHERAPY, ILLUSTRATION

Illustration of CAR (chimeric antigen receptor) T cell immunotherapy, a process that is being developed to treat cancer. T cells (shown in cross-section), part of the body's immune system, are taken from the patient and have their DNA (deoxyribonucleic acid) modified by viruses (round) so that they produce chimeric antigen receptor (CAR) proteins (green). These proteins will be specific to the patient's cancer. They have an extracellular receptor component and an internal signalling and co-stimulatory domain. The modified T cells are then multiplied in the laboratory before being reintroduced to the patient. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

SICKLE CELL ANAEMIA, ILLUSTRATION

Illustration of red blood cells affected by sickle cell anaemia (foreground) and some healthy red blood cells (background). Sickle cell anaemia is an inherited blood disease in which the red blood cells contain an abnormal form of haemoglobin (blood's oxygen-carrying pigment, green and purple) that causes the blood cells to become sickle-shaped, rather than round. Sickle cells cannot move through small blood vessels as easily as normal cells and so can cause blockages. This prevents oxygen from reaching the tissues, causing severe pain and organ damage. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

SICKLE CELL ANAEMIA, ILLUSTRATION

Illustration of red blood cells affected by sickle cell anaemia (brown) and some healthy red blood cells (red). Sickle cell anaemia is an inherited blood disease in which the red blood cells contain an abnormal form of haemoglobin (blood's oxygen-carrying pigment, blue and pink) that causes the blood cells to become sickle-shaped, rather than round. Sickle cells cannot move through small blood vessels as easily as normal cells and so can cause blockages. This prevents oxygen from reaching the tissues, causing severe pain and organ damage. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

CRISPR TREATMENT FOR SICKLE CELL ANAEMIA, CONCEPTUAL ILLUSTRATION

CRISPR treatment for sickle cell anaemia, conceptual illustration. Red blood cells affected by sickle cell anaemia (red and white) having their DNA (deoxyribonucleic acid, green double helix) repaired using CRISPR-Cas9 gene editing. Sickle cell anaemia is an inherited blood disease in which the red blood cells contain an abnormal form of haemoglobin (blood's oxygen-carrying pigment) that causes the blood cells to become sickle-shaped, rather than round. Sickle cells cannot move through small blood vessels as easily as normal cells and so can cause blockages. This prevents oxygen from reaching the tissues, causing severe pain and organ damage. The first CRISPR treatments for sickle cell anaemia were approved in the UK and USA at the end of 2023. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

CAR T CELL IMMUNOTHERAPY, ILLUSTRATION

Illustration of CAR (chimeric antigen receptor) T cell immunotherapy, a process that is being developed to treat cancer. T cells (shown in cross-section), part of the body's immune system, are taken from the patient and have their DNA (deoxyribonucleic acid) modified by viruses (round) so that they produce chimeric antigen receptor (CAR) proteins (blue). These proteins will be specific to the patient's cancer. They have an extracellular receptor component and an internal signalling and co-stimulatory domain. The modified T cells are then multiplied in the laboratory before being reintroduced to the patient. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

SICKLE CELL ANAEMIA, ILLUSTRATION

Illustration of red blood cells affected by sickle cell anaemia (brown) and some healthy red blood cells (red). Sickle cell anaemia is an inherited blood disease in which the red blood cells contain an abnormal form of haemoglobin (blood's oxygen-carrying pigment, blue and pink) that causes the blood cells to become sickle-shaped, rather than round. Sickle cells cannot move through small blood vessels as easily as normal cells and so can cause blockages. This prevents oxygen from reaching the tissues, causing severe pain and organ damage. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)

CRISPR TREATMENT FOR SICKLE CELL ANAEMIA, CONCEPTUAL ILLUSTRATION

CRISPR treatment for sickle cell anaemia, conceptual illustration. Red blood cells affected by sickle cell anaemia (red and white) having their DNA (deoxyribonucleic acid, blue double helix) repaired using CRISPR-Cas9 gene editing. Sickle cell anaemia is an inherited blood disease in which the red blood cells contain an abnormal form of haemoglobin (blood's oxygen-carrying pigment) that causes the blood cells to become sickle-shaped, rather than round. Sickle cells cannot move through small blood vessels as easily as normal cells and so can cause blockages. This prevents oxygen from reaching the tissues, causing severe pain and organ damage. The first CRISPR treatments for sickle cell anaemia were approved in the UK and USA at the end of 2023. (KEYSTONE/SCIENCE PHOTO LIBRARY/KEITH CHAMBERS)