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Charles Best (left) and Frederick Banting (right), Canadian physiologists and co- discoverers of the hormone insulin, standing with the first dog kept alive by insulin injections following the removal of its pancreas. In 1921, Banting (1891-1941) devised a method of obtaining insulin, the hormone found in the pancreas and thought to be connected with diabetes mellitus. He carried out his research with an assistant, Best (1899-1978). In 1922, Banting and Best isolated the hormone insulin and proved its connection with diabetes. The following year, Banting won the Nobel prize. Banting shared the prize with Best, who Banting felt had been cheated. (KEYSTONE/SCIENCE PHOTO LIBRARY/Str)